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Mass Spectrometry

Techniques & Tools Pharma & Biopharma

Electrifying Analysis in R&D

| Mark R. Taylor, Susana Da Silva Torres

Electrochemical reaction cells are finding new applications in the pharma R&D lab that could offer big time and cost savings. Here, we share our experiences using electrochemistry with on-line mass spectrometry to study pharmaceutical stability and oxidation products – and explain why we’re electrochemistry converts.

Techniques & Tools Forensics

Adding Science Behind the Canine

| John DeHaan, Gareth S. Dobson, David Matthew

Leveraging technology solutions to support rather than replace dogs in arson investigations.

Techniques & Tools Genomics & DNA Analysis

Jurassic Park Parchment

| Stephanie Vine

DNA from ancient archive gives researchers a window into animals of the past

Techniques & Tools Mass Spectrometry

Finding Phytase

| Stephanie Vine

Recombinant blood protein contamination is discovered by chance. NMR to the rescue?

Fields & Applications Sample Preparation

Measuring protein molecular weight using the Viscotek SEC-MALS 20 connected to a Waters Empower® SEC system

In this application note, we show that Malvern’s OmniSEC software can now communicate with Waters Empower® for the seamless exchange of sample sequences. A selection of proteins was used to demonstrate the measurement of protein molecular weight, oligomeric and aggregation state.

Fields & Applications Sample Preparation

PEGylated proteins: Optimizing conjugation reactions using triple detection SEC

In this application note, one protein, interferon α-5, was conjugated with two different PEG molecules in different reactions.  The protein and PEG molecules were characterized individually using multi-detector SEC, followed by the PEGylated conjugates.  Their composition, molecular weights and intrinsic viscosities were measured. This work was performed by Celares GMBH, Germany with samples provided by DIGNA BIOTECH, Spain

Techniques & Tools Mass Spectrometry

How to Get PR Right

| Marcus Lippold

How do your customers, your competitors, the press or even the public perceive your organization? Here, I offer my tips, tricks and thoughts on PR – and suggest why you might want to consider a smarter approach.

Fields & Applications Mass Spectrometry

When Great Minds Think Alike

| Rich Whitworth

The M908 took the top spot in our 2013 Innovation Awards – “Revolutionary technology; will be an inspiration for new generations,” said the judges. Here, four co-founders of 908 Devices describe the perfect storm that led to the creation of the world’s first handheld mass spectrometer.

Techniques & Tools Mass Spectrometry

Innovation Showcase

Sponsor companies proudly present their impressive contributions to the analytical science community.

Techniques & Tools Technology

Return of the TASIAs

| Rich Whitworth

Accurate measurement drives progress in science in immeasurable ways. Here, we celebrate a year’s worth of advances in The Analytical Scientist Innovation Awards 2014. What impact will these 15 TASIA winners have on your field?

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