Mass Spectrometry

In water analysis, direct injection of samples into your LC-MS/MS system (without sample preparation beyond filtration) is possible because of advances in instrumentation. However, matrix effects must be monitored carefully – and sometimes may even prove useful.

GSK and the RSC embark on a five-year partnership to bring GC-MS skills to Africa

A new LC-MS/MS screening method simultaneously detects a wide range of non-banned potentially performance enhancing drugs and masking agents in urine

Three years on, and our mission to record, celebrate and scrutinize analytical science is as strong as ever.

This application note will describe the analysis of a series of dextran samples ranging in molecular weight from about 1 – 650 kDa. Structural comparisons to other polysaccharides, gum arabic and pectin are presented. Initially discovered by Louis Pasteur in 1861, dextran is a polysaccharide that has found a variety of applications, primarily in the medical field, due to its minimal side-effects and solubility in aqueous media.

Sitting Down With… Detlef Günther, VP Research and Corporate Relations, and Professor for Trace Element and Micro Analysis, ETH Zürich, Switzerland.

Coupling whole column imaging detection to a mass spectrometer for protein structure characterization is fundamentally challenging. Could a relatively simple capillary cartridge system unlock the potential?

Capillary electrophoresis-mass spectrometry (CE-MS) appears to be caught in a dichotomy – proven success in some fields, skepticism in others.

A growing target list, increasingly complex matrices, and the need for low limits of detection can make our field seem like an uphill treadmill.

Thin-layer chromatography’s ability to simply and inexpensively provide high-quality separations in parallel makes it the perfect partner for MALDI mass spectrometry