Sample Preparation

The Thermo Scientific™ SMART Digest™ ImmunoAffinity (IA) Kits are designed for biomarker and bio-therapeutic characterization and quantitation

Given ongoing challenges in sample preparation, is it time to give LPME a second chance?

Our experts select and reflect on six standout papers that advanced analytical science in 2016.

Is your viscometer approaching the end of its life? Are you starting to feel that your trial and error, ‘rheology-light’ approach to formulation is becoming dated? Or are there longstanding product performance issues that you’re failing to gain traction with, where you suspect rheology may hold the answer?

This application note describes a selection of measurements made on a GE AKTA basic system.

Laser diffraction and dynamic light scattering enable the identification of an optimal particle size distribution for dairy emulsions to support the cost-effective manufacture of high quality products.

In this article we take an introductory look at work carried out by TU Clausthal to develop an improved understanding of the mechanisms of enhanced oil recovery (EOR) by polymer flooding, and the relevance of fluid rheology. Example data illustrates the insight that rheology provides and its application in optimizing fluid performance.

In particular, this article demonstrates the correlation between molecular changes (Raman Spectroscopy) and microstructural evolution of rheological properties (DLS, DLS-optical microrheology) for the first time for surfactant-based wormlike micellar system. Whereby, Raman Spectroscopy provides information about the molecular structure and DLS-microrheology characterizes viscoelastic properties, the combination of data delivered allows for a deeper understanding of the molecular changes underlying the viscoelastic ones. The study illustrates the utility of the combined DLS, DLS-optical microrheology and Raman Spectroscopy in providing new molecular structural insights into the self-assembly process in complex fluids.

Sample preparation challenges in the modern biopharmaceutical laboratory

Takayuki Kawai asks: how do we best accomplish analysis of extremely low volume samples?