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Sample Preparation

Fields & Applications Sample Preparation

Automated particle size with Zetasizer NanoSampler

The Zetasizer NanoSampler is a sample delivery system that ensures highly precise and reproducible automated loading of samples into your Zetasizer Nano for particle size measurements. The NanoSampler adds automation and unattended operation in a versatile, compact package, maximising the productivity of your Zetasizer Nano.

Fields & Applications Sample Preparation

Differentiation and characterization of subvisible particulates in therapeutic protein products

This application note provides an example of how Archimedes can be used to detect and quantify the formation of protein sub-visible particles and the introduction of silicone oil droplets, in response to shear stress.

Fields & Applications Sample Preparation

Overcoming the negative effect of protein structure on molecular weight measurement by Size Exclusion Chromatography

In this application note we will look at two examples where the retention volume of a sample could not be used to obtain an accurate measure of the sample MW. We will also describe the additional information that can be obtained using these advanced detectors. This work has been performed in conjunction with the Institut Pasteur, Paris, France

Techniques & Tools Sample Preparation

Characterization of Branded Co-Polymers by Triple Detection GPC

| Sponsored by Malvern Panalytical

Polymers can be loosely grouped into two structural categories – linear and branched.

Techniques & Tools Sample Preparation

Analysis of Membrane Protein by Multi-Detector SEC

Work performed in conjunction with the Membrane Protein Laboratory, Imperial College, London

Fields & Applications Sample Preparation

When only a MALS detector will do…

Light scattering detectors play an important role in gel permeation chromatography and size exclusion chromatography (GPC/SEC) analysis because of their ability to directly measure molecular weight distribution. Multi angle light scattering (MALS) detectors are often chosen, in some instances because they provide the most accurate data for the measurement of the radius of gyration (Rg), and in others because they have become an accepted industry standard. The launch of Malvern Instruments’ new Viscotek SEC-MALS 20 detector extends commercial choice in this area and draws the technology into the spotlight.

Techniques & Tools Pharma & Biopharma

Back to School for Pharmaceutical Analysis

| W. Franklin Smyth

Deeper consideration of individual analytical unit processes offers a more systematic approach to method development, ensuring that we don’t forget the basics in an increasingly sophisticated world.

Fields & Applications Sample Preparation

The Solution Evolution

| Rich Whitworth

Agilent Technology’s Markets and Applications Programs – MAPs for short – connect you to a growing network of expertise to provide working solutions for your analytical business.

Fields & Applications Environmental

Proteins At Work

| Albert Heck, Reinout Raaijmakers

How we can best provide state-of-the-art proteomics technology to the biomedical community.

Techniques & Tools Environmental

Greening Analytical Science

| Miguel de la Guardia Cirugeda

How we might reduce environmental impact without reducing capability – and why we should try

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