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February 2015 Issue of The Analytical Scientist

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Articles featured in this issue

Techniques & Tools Mass Spectrometry

Clinical Collaborations

| Rich Whitworth

Is analytical science poised to storm the theatre and steal the spotlight? Possibly not. But I do sense an increasingly central – and recognized – role, particularly in the clinic.

Techniques & Tools Spectroscopy

Skeleton Crew

| Stephanie Vine

Raman spectroscopy identifies rickets in 400-year-old bones from the Mary Rose

Fields & Applications Food, Beverage & Agriculture

Sniffing Out Chirality

| Stephanie Vine

Odorant binding proteins could help to unlock new biosensors

Techniques & Tools Clinical

Surgical Spectroscopy

| Stephanie Vine

A UK study is set to examine whether new Raman technology can be used to assist surgeons during brain tumor removal.

Techniques & Tools Mass Spectrometry

Pittcon Prelude / Editor’s Top Fives

| Stephanie Vine

Ahead of New Oleans, we offer a little history, editorial program picks, and invite you to the Humanity in Science Award symposium.

Fields & Applications Clinical

The 100,000 Genomes Project

| Stephanie Vine

An ambitious UK sequencing project aims to learn more about patients with cancer and rare diseases

Fields & Applications Technology

Graduating from the Physical to the Chemical

| Joshua Windmiller

Why analytical chemistry must be leveraged in the next generation of wearable devices.

Techniques & Tools Sample Preparation

Polishing Your Injection Technique

| Jaap de Zeeuw

There are a lot of things to consider when seeking good results from gas chromatography. Success often comes from understanding precisely what goes on in the injection port.

Fields & Applications Pharma & Biopharma

Beyond the Champions League

| Cari Sänger-van de Griend

We’re looking for analytical players for a new fixture on the calendar – Analytical Technologies Europe 2015. Together we can beat the challenges of the biopharmaceutical industry.

Techniques & Tools Mass Spectrometry

The Beginner’s Guide to ICP-MS

| Robert Thomas

You’ve convinced your boss that your laboratory absolutely needs a shiny new quadrupole-based, inductively coupled plasma mass spectrometry (ICP-MS) system for trace element analysis. Now what?

Techniques & Tools Technology

How to Win at LIMS

| Brad Lord

Implementing a new laboratory information management system (LIMS) takes a lot more work than choosing the “right” software.

Fields & Applications Mass Spectrometry

Pioneers of Precision Medicine

| Jeremy Nicholson

At the heart of the drive for increased epidemiological knowledge, faster diagnostics and better-informed treatment decisions are collaborations between medical doctors and analytical specialists.

Fields & Applications Mass Spectrometry

MultiModal Molecular Imaging

| Ron M. A. Heeren

Molecular imaging based on mass spectrometry provides a broad scope of analytical, molecular and local information that can be employed for patient phenotyping.

Fields & Applications Mass Spectrometry

The Surgeon’s Perspective

| Steven Olde Damink

The primary value of M4I really lies in the investment in human capital (rather than simply MSI hardware)

Techniques & Tools Metabolomics & Lipidomics

Gurus of the monolith

| Emily Hilder, Sebastiaan Eeltink, Frantisek Svec, Nobuo Tanaka

Four stationary phase experts – Emily Hilder, Frantisek Svec, Nobuo Tanaka and Sebastiaan Eeltink – discuss the unfolding story of monolithic columns: from chromatographic curiosity to the future of sample preparation?

Techniques & Tools Technology

Microscale LC-MS for the Masses

| Peter Claise

How The Analytical Scientist Innovation Award (TASIA) winning ionKey/MS System made ultra-sensitive liquid chromatography-mass spectrometry (LC-MS) ultra accessible.

Techniques & Tools Mass Spectrometry

Qual and Quant MS: The Perfect Marriage

| Rich Whitworth

Let’s go back to the early 1990s when an important innovation was starting to cause a stir. Electrospray ionization (ESI) essentially allowed liquid chromatography (LC) and mass spectrometry (MS) to be combined much more easily as an analytical technique.

Techniques & Tools Mass Spectrometry

Racing Ahead in Innovation

| Oscar van den Brink

Oscar van den Brink, managing director of COAST and TKI-Chemistry in the Netherlands.

Techniques & Tools Spectroscopy

Sorting Out Gluten Intolerance

| Sponsored by Ocean Optics

NIR spectroscopy and machine vision team up for rapid grains inspection

Techniques & Tools Liquid Chromatography

Tea with Wolfgang Lindner

| Wolfgang Lindner

Wolfgang discusses the spirit of science, Salzburg and ISC2014 in the latest episode of Tea with Rich.

Business & Education Chemical

Tea with Peter Schoenmakers

| Peter Schoenmakers

How does a young scientist get on the ‘team’? Peter Schoenmakers offers his advice, while Rich offers tea.

Fields & Applications Clinical

Tea with Michael Lämmerhofer

| Michael Lämmerhofer

Michael Lämmerhofer opens up about his work on oxidative stress markers and the Chromatographic Society’s Jubilee Award.

Fields & Applications Sample Preparation

The big reveal: Workhorse + Innovation = more information (Part 1)

A concern raised by the rise in routine MRI screening within the healthcare industry is that the ability to detect abnormalities within the body may currently be running ahead of our understanding of their possible consequences, making it difficult to determine a sound course of action. Here then analytical science is arguably advancing beyond current requirements.

Fields & Applications Sample Preparation

The big reveal: Workhorse + Innovation = more information (Part 2)

In this second article of a short series Dr Paul Kippax is looking at the how recent innovations are substantially enhancing the value and informational productivity of some of our established and trusted analytical techniques. This time, the addition of multiple detectors to a GPC/SEC analysis…

Techniques & Tools Sample Preparation

The big reveal: Workhorse + Innovation = more information (Part3)

| Sponsored by Malvern Panalytical

In this short series of articles Dr Paul Kippax is looking at how recent innovations are substantially enhancing the value and informational productivity of some of our established and trusted analytical techniques. This time, the addition of Raman spectroscopy to automated imaging…

Fields & Applications Sample Preparation

The Mark–Houwink plot – Differentiation of Branching and Composition

Using OMNISEC, we will show how to separate the effects of a structural difference induced by a compositional change to a polymer (e.g. substitution) and the structural change induced by polymer chain branching.

Other issues of 2015