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Fields & Applications Sample Preparation

Microcalorimetry as a tool for structural biology

Learn how Isothermal titration calorimetry can be used to guide protein (RNA)/ligand crystallization and to resolve common issues with crystallization of complexes.

Fields & Applications Sample Preparation

Characterization of IgG monomers & their aggregates

Determining the components, and their proportion, in a protein sample is essential for the improvement of candidate formulations and characterization of final formulations.

Techniques & Tools Microscopy

When Art Meets Science

| Frank van Geel

Welcome to our second foray into the fascinating confluence of aesthetics and analytics, where we celebrate the wonderful and diverse world of analytical science by sharing your spectacular images.

Techniques & Tools Spectroscopy

Unraveling Art with Analysis

| Stephanie Sutton

SORS meets microscopy to delve deeper into historical art and sculptures

Techniques & Tools Microscopy

Rewarding Lab Effectiveness and Efficiency

| Peter James

S-Lab is using an awards scheme, an annual conference, and assessment tools and guidance to drive improvement in areas that are common to both analytical and research laboratories.

Techniques & Tools Technology

The Big Picture

| Rich Whitworth

In the quest for increased sensitivity or higher resolution, let’s not lose sight of our objectives.

Fields & Applications Sample Preparation

Detecting agglomerates within pharmaceutical formulations

Particle agglomeration can compromise the clinical efficacy of pharmaceutical products and must therefore be closely controlled. Automated particle image analysis provides one technology which can aid agglomerate detection. This article provides practical guidance on how imaging can be applied as a routine method to robustly identify and quantify the state of agglomeration of pharmaceutical formulations.

Techniques & Tools Mass Spectrometry

Single-Molecule Mass Spec with Inertial Imaging

| Stephanie Sutton

Conventional mass spectrometry can only measure the mass of a molecule – what if you could image the same molecule simultaneously?

Techniques & Tools Genomics & DNA Analysis

Gurus of Single Molecule Detection

| David Duffy, Ulf Landegren, Antoine van Oijen, and Menno Prins

David Duffy, Ulf Landegren, Antoine van Oijen, and Menno Prins crash through the concentration barrier and investigate the ultimate limit of analytical sensitivity.

Techniques & Tools Mass Spectrometry

Pittcon Prelude / Editor’s Top Fives

| Stephanie Sutton

Ahead of New Oleans, we offer a little history, editorial program picks, and invite you to the Humanity in Science Award symposium.

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